To Use the Core

For instructions about how to use the Core, click here.

Results 

We have a new data portal  to access your results! 
News

  • MicroRNA

    MicroRNA Expression Profiling

    TaqMan-based quantification of human or rodent microRNAs is being offered as a research service by the DFCI Molecular Diagnostics Laboratory.

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  • Next Gen Sequencing

    A Higher Resolution

    Whole genome and whole transcriptome sequencing and massively parallel, ligation-mediated, dibase-encoding platform. 

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  • Mouse SNP Array

    Mouse Genotyping and Copy Number

    A single array that genotypes ~600,000 dimorphic loci and also has ~900,000 "copy number" probes.

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  • Improved Specificity

    Gene 1.0 ST and Exon Arrays

    The processing protocol for the Gene 1.0ST and Exon arrays has been modified; "random" primers have been depleted of rRNA sequences.

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  • RNA for 3' Arrays

    Submit Less RNA

    The "Affymetrix processing" protocol for 3' arrays has been modified: much less RNA is needed.

    Read More...

Microarray Core

Our Pricing has been updated and is in effect as of April 22, 2013. Price List . 

Array-based services include gene expression profiling on 3' arrays, Exon 1.0 ST arrays, and on Gene 1.0 ST arrays; genotyping and comparative genomic hybridization both on single nucleotide polymorphism (SNP) arrays, and Chromatin ImmunoPrecipitation localization (ChIP-on-Chip) on tiling arrays. All services use oligonucleotide microarrays. Next Generation Sequencing (NGS) services include DNA-based and RNA-based applications. Biostatistical support to assist in analyzing the data is available. The services of the Core are accessible to DFCI investigators and to investigators outside of DFCI.

Laboratory

The laboratory analyses begin with RNA or DNA, provided by investigators, and produce scan data (microarrays) or sequence data (NGS) along with quality control data. These data are available via password-protected accounts accessible through this web site.

Biostatistics

Biostatistical Support is available at the facility to educate investigators about approaches and tools for microarray and NGS data analysis. Assistance with concepts and software.

Pricing

Instrumentation, computers and other start-up costs have been provided by the generosity of donors. The pricing structure for laboratory analyses consists of two tiers - one for DFCI investigators, and another for investigators outside of DFCI.